Molecular Formula | C34H59N3O9 |
Molar Mass | 653.85 |
Density | 1.031±0.06 g/cm3(Predicted) |
Melting Point | 178.5 °C |
Boling Point | 833.8±65.0 °C(Predicted) |
Solubility | DMSO: soluble10mg/mL |
Appearance | White to off-white crystalline solid. |
pKa | -1.45±0.70(Predicted) |
Storage Condition | -20°C |
In vitro study | CCF-STTG1 cells are sensitive to Enniatin B1 (IC 50 =4.4 μM). |
Hazard Symbols | T - Toxic |
Risk Codes | 23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. |
Safety Description | 45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
UN IDs | 2811 |
WGK Germany | 3 |
Hazard Class | 6.1(a) |
Packing Group | I |
introduction | Enniatin B1 (fusarium B1) is a Fusarium toxin. In rat liver microsomal enzyme experiment, Enniatin B1 inhibited acyl-CoA: cholesterol acyltransferase (ACAT) activity with IC50 of 73 μM. Enniatin B1 can penetrate the blood-brain barrier. Enniatin B1 reduces ERK (p44/p42) activation. Enniatin B1 inhibited TNF-α-induced NF-κB activation. |
biological activity | Enniatin B1 is a Fusarium toxin. In rat liver microsomal enzyme experiments, Enniatin B1 inhibited acyl-CoA: cholesterol acyltransferase (ACAT) activity with an IC50 of 73 μM. Enniatin B1 can penetrate the blood-brain barrier. Enniatin B1 reduces ERK (p44/p42) activation. Enniatin B1 inhibited TNF-α-induced NF-κB activation. |
target | ACAT ERK NF-κB |
in vitro study | CCF-STTG1 cells are sensitive to Enniatin B1 (IC 50=4.4 μM). |